The International Security Forum Bonn is a high-level international event to ensure a dialogue on current foreign and security policy issues. This year’s forum focused on the challenges arising from changes in transatlantic relations, the upcoming global geo-economic and geopolitical obstacles, and the crises caused by the Covid-19 pandemic. As part of the panel „Aftermath: The Geopolitics of the Pandemic – Trend Multiplier of Game Changer?“ the Director of the DIE Prof. Dr. Anna-Katharina Hornidge discussed with five other participants the consequences of the pandemic with regard to geopolitical issues. The conference closed with a virtual dinner lecture by the virologist Prof. Dr. Hendrik Streeck of the University of Bonn. The dinner debate provided an opportunity to discuss HIV-related health infrastructures in Africa regarding their positive role in dealing with Covid-19.